Comparison of Pre- and Postoperative Lower Urinary Tract Symptoms and Quality of Life After Pelvic Organ Prolapse Surgery

Malik A1

Research Type

Clinical

Abstract Category

Pelvic Organ Prolapse

Abstract 723
Open Discussion ePosters
Scientific Open Discussion Session 108
Saturday 20th September 2025
13:45 - 13:50 (ePoster Station 5)
Exhibition
Pelvic Organ Prolapse Prospective Study Quality of Life (QoL) Questionnaire Surgery
1. AGA Khan University Hospital Karachi Pakistan
Presenter
Links

Abstract

Hypothesis / aims of study
Pelvic organ prolapse (POP) is frequently associated with lower urinary tract symptoms (LUTS), significantly impacting women's quality of life (QOL) [1]. Surgical correction of POP may lead to either resolution or emergence of de novo LUTS postoperatively [2]. This study uses standardized assessment tools to evaluate trends in LUTS and QOL improvements before and after POP surgery
Study design, materials and methods
This prospective study included 51 women with POP-Q stage II or greater undergoing pelvic reconstructive surgery. LUTS and QOL were assessed preoperatively and at 1 week, 1 month, and 6 months postoperatively using validated questionnaires: the International Consultation on Incontinence Questionnaire – Female Lower Urinary Tract Symptoms (ICIQ-FLUTS) and Pelvic Floor Impact Questionnaire (PFIQ-7). Surgical interventions followed standardized protocols, and data were analyzed using SPSS 19.0. Statistical tests included the Friedman test for repeated measures and the Wilcoxon test for multiple comparisons, with p ≤ 0.05 considered statistically significant [3].
Results
The mean age of participants was 60.37 ± 11.87 years. Vaginal hysterectomy with McCall’s culdoplasty and anterior-posterior repair was the most performed procedure (61%). Preoperatively, LUTS were highly prevalent, including nocturia (84.3%), urgency (74.5%), and hesitancy (96.1%). At six months postoperatively, significant symptom resolution was observed in nocturia (39.53% complete resolution, p < 0.0005), urgency (50% resolution, p <0.0005), and hesitancy (95.9% resolution, p < 0.0005). The mean ICIQ-FLUTS score significantly decreased from 10.67 ± 5.14 preoperatively to 2.27 ± 2.39 postoperatively (p < 0.0005). The mean PFIQ-7 score improved from 88.89 ± 54.87 to 8.57 ± 18.37 (p < 0.0005), indicating substantial enhancement in QOL. De novo stress urinary incontinence (SUI) developed in three patients.
Interpretation of results
This study demonstrates a significant reduction in storage, voiding, and incontinence symptoms following POP surgery, with notable improvements in QOL. While some patients developed de novo SUI, overall LUTS improved in the majority. These findings emphasize the need for preoperative counselling regarding LUTS outcomes and individualized patient management
Concluding message
POP surgery significantly improves LUTS and QOL, supporting its role in enhancing urinary health and patient well-being. This first prospective study from Pakistan underscores the importance of preoperative counselling regarding LUTS outcomes and supports the role of POP surgery in improving QOL
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References
  1. 1. De Boer, T.A., Slieker-ten Hove, M.C., Burger, C.W., Vierhout, M.E., & Kluivers, K.B. (2010). Pelvic organ prolapse and overactive bladder. Neurourology and Urodynamics, 29(1), 30-39.
  2. 2. Ugianskiene, A., Petros, P., & Jauniskis, L. (2017). Retrospective study on de novo postoperative urinary incontinence after pelvic organ prolapse surgery. European Journal of Obstetrics & Gynecology and Reproductive Biology, 219, 10-14.
  3. 3. Barber, M.D., Walters, M.D., & Bump, R.C. (2005). Short forms of two condition-specific quality-of-life questionnaires for women with pelvic floor disorders (PFDI-20 and PFIQ-7). American Journal of Obstetrics and Gynecology, 193(1), 103-113.
Disclosures
Funding none Clinical Trial No Subjects Human Ethics Committee The institutional ethics research committee (ERC) of Aga Khan University Hospital (AKUH) Karachi Pakistan Helsinki Yes Informed Consent Yes
16/07/2025 12:03:40